Angiotensin-Converting Enzyme 2 Potentiates SARS-CoV-2 Infection by Antagonizing Type I Interferon Induction and Its Down-Stream Signaling Pathway

ABSTRACT The innate interferon (IFN) response constitutes the first line of host defense against viral infections.It has been shown that IFN-I/III treatment could effectively contain severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in vitro.However, how SARS-CoV-2 survives through the innate antiviral mechanism remains to be

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Genome and Transcriptome of Clostridium phytofermentans, Catalyst for the Direct Conversion of Plant Feedstocks to Fuels.

Clostridium phytofermentans was isolated from forest soil and is distinguished by its capacity to directly ferment plant cell wall Blue Bottle Lamp Gift Box polysaccharides into ethanol as the primary product, suggesting that it possesses unusual catabolic pathways.The objective of the present study was to understand the molecular mechanisms of bio

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Co-Infection of Tobacco Rattle and Cycas Necrotic Stunt Viruses in Paeonia lactiflora: Detection Strategies, Potential Origins of Infection, and Implications for Paeonia Germplasm Conservation

Increasing reports of tobacco rattle virus (TRV) and cycas necrotic stunt virus (CNSV) in herbaceous Paeonia worldwide highlight the importance of conserving the genetic resources of this economically important ornamental and medicinal crop.The unknown origin(s) of infection, differential susceptibility shoe of peony cultivars to these viruses, and

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